Skip to main content
Harper Adams University logo


    BBSRC LBNet Early Stage Career Fellowship: Harnessing anaerobic deconstruction of wheat straw for fuel, platform chemicals and bio-degrading enzymes (ADconstraw)


    The aim of this work is to combine metagenomic and metaproteomic analyses to determine the genetic code and protein synthesis which underlies the mechanisms of wheat straw (WS) deconstruction by anaerobes native to sewage sludge. The untapped ecosystem will be mined for previously undiscovered enzymes with the potential for use in lignocellulose bio-refineries as green alternatives to chemical pre-treatments. Enzyme discovery will be facilitated by the application of a biotin-tagging method that has recently been developed to purify and identify secreted enzymes which bind to WS. Biotin-tagging overcomes the practical challenge of contamination by intracellular proteins caused by the aggression of extraction procedures which are necessary to detach the enzymes of interest from their lignocellulosic substrates.



    Funding Body


    Lead Organisation

    Harper Adams University


    University of York & Durham University

    Cookies on the Harper Adams University website

    We use cookies to ensure that we give you the best experience on our website. If you continue without changing your settings, we'll assume that you are happy to receive all cookies on the website. However, you can change your cookie settings at any time.